Designed especially for neurobiologists, FluoRender is an interactive tool for multi-channel fluorescence microscopy data visualization and analysis.
Large scale visualization on the Powerwall.
BrainStimulator is a set of networks that are used in SCIRun to perform simulations of brain stimulation such as transcranial direct current stimulation (tDCS) and magnetic transcranial stimulation (TMS).
Developing software tools for science has always been a central vision of the SCI Institute.

Events on March 20, 2017

Imaging Seminar

Shireen Elhabian Presents:

From Silhouettes to Generative Shape Models: A Variational Bayesian Learning Approach

March 20, 2017 at 12:00pm for 1hr
Evans Conference Room, WEB 3780
Warnock Engineering Building, 3rd floor.



Shape models provide a compact parameterization of a class of shapes, and have been shown to be important to a variety of medical and vision problems, including object detection, tracking, registration, and image segmentation. Learning generative shape models from grid-structured representations, aka silhouettes, is usually hindered by (1) data likelihoods with intractable marginals and posteriors, (2) high-dimensional shape spaces with limited training samples (and the associated risk of overfitting), and (3) estimation of hyperparameters relating to model complexity that often entails computationally expensive grid searches. Here, we propose a Bayesian treatment that relies on direct probabilistic formulation for learning generative shape models in the silhouettes space. We propose a variational approach for learning a latent variable model in which we make use of, and extend, recent works on variational bounds of logistic-Gaussian integrals to circumvent intractable marginals and posteriors. Spatial coherency and sparsity priors are also incorporated to lend stability to the optimization problem by regularizing the solution space while avoiding overfitting in this high-dimensional, low-sample-size scenario. We deploy a type-II maximum likelihood estimate of the model hyperparameters to avoid grid searches. We demonstrate that the proposed model generates realistic samples, generalizes to unseen examples, and is able to handle missing regions and/or background clutter, while comparing favorably with recent, neural-network-based approaches. 

Posted by: Blake Zimmerman