The NIH/NIGMS
Center for Integrative Biomedical Computing

CIBC Collaboration

Collaboration and service are integral to the success of our Center. The collaborations we foster have the potential to lead to Driving Biomedical Projects which, in turn, influence the TR&D research. The evidence for successful collaborations is seen in the Centers publication numbers and cited software. These collaborations would not be possible if we did not rely heavily on our service infrastructure to provide a mechanism for reaching out to a broad community of users. While our practice has proved effective, this process is challenging due to the remote location of many of our users, the limited electronic interactions, and the cross cutting research areas our collaborators come from.

cone-of-influenceTo address these challenges, we have developed a systematic series of stages we can use to identify potential collaborators as well as make use of our Driving Biomedical Project Research Clusters to attract collaborators. First, we actively identify motivated users through our mailing lists, bug fix requests, contact request forms, and workshop and training events. Through those interactions, we can quickly identify the type of service a user might need. These types of services can be a simple as identifying a tutorial or pointing at an example dataset for a particular software program, or as involved as setting up multiple one-on-one meetings to address a specialized need. Through these interactions we build our collaborative base and learn more about the requirements of the research community. The Center can then choose to address these needs as new features in our software. In addition to identifying individual research needs, we envision our research clusters as a way of reaching out to a broader community of researchers. The clusters translate problems for a small community into a larger area of interest, which in turn fosters more collaboration. We see these combined efforts of reaching out to users and researchers through service, while also exploiting the Research Clusters, as an advertising mechanism for attracting new collaborations.

 

The Collaboration Pipeline

collaborator-pipe

 


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Biomedical Research Cluster 1: Microscopy and Small Scale Imaging Collaborators

Collaborating PI: Balamurali Ambati, M.D., Ph.D.
Institution: Moran Eye Center, University of Utah
Title of Project: Targeted Intraceptor Nanoparticle Therapy Reduces Angiogenesis and Fibrosis in Primate & Murine Macular Degeneration
Publications

Collaborating PI: Jennifer Dy, Ph.D.
Institution: Northeastern University
Title of Project: Image segmentation for confocal microscopy
Publications

Collaborating PI: Mark Ellisman, Ph.D.
Institution: National Center for Microscopy and Imaging Research (NCMIR)
Title of Project: EM image processing and visualization
Publications

Collaborating PI: Bryan Jones, Ph.D.
Institution: Moran Eye Center, University of Utah
Title of Project: Volume rendering of models of the circuitry of the mammalian retina
Publications

Collaborating PI: Leslie Loew, Ph.D., and Ion Moraru, Ph.D.
Institution: The National Resource for Cell Analysis and Modeling (NRCAM), University of Connecticut Health Center
Title of Project: Image based modeling in cell simulations
Publications

Collaborating PI: Milind Rajadyhaksha, Ph.D.
Institution: Memorial Sloan Kettering Cancer Center (MSKCC), New York
Title of Project: Confocal imaging of skin, oral cavity, and breast tissue
Publications

Biomedical Research Cluster 2: Biomechanics and Blood Flow Collaborators

Collaborating PI: Kent Bachus, Ph.D.
Institution: University of Utah, Dept. of Orthopaedics
Title of Project: Population-based analysis for optimal design of percutaneous os- seointegrated docking systems
Publications

Collaborating PI: Heath Henninger, Ph.D.
Institution: Department of Psychiatry, University of North Carolina
Title of Project: Morphological analysis of shoulder pathoanatomy
Publications

Collaborating PI: Kevin Jones, M.D.
Institution: Dept. of Orthopaedics, Huntsman Cancer Institute, University of Utah
Title of Project: Morphological analysis of cell transition in sarcomas
Publications

Collaborating PI: Murat Maga, Ph.D.
Institution: University of Washington, Dept. of Pediatrics
Title of Project: Morphological analysis of cranial/facial phenotypes and developmental models in rodents
Publications

Collaborating PI: Sandra Shefelbine, Ph.D. (PI), Young-Jo Kim, M.D., Ben Shore, M.D., M.P.H., Sarah Bixby M.D., Cara Lewis, Ph.D., P.T.
Institution: Northeastern University, Boston Children's Hospital, Boston University
Title of Project: Altered physeal development in young athletes: what causes femoroacetabular impingement?
Publications

Biomedical Research Cluster 3: Neuromodulation and Brain Source Localization Collaborators

Collaborating PI: Deniz Erdogmus, Ph.D.
Institution: Northeastern University
Title of Project: EEG-sensing, TDCS-stimulation system
Publications

Collaborating PI: Brad Manor, Ph.D.
Institution: Institute for Aging Research, Harvard Medical School
Title of Project: Modulating brain activity to preserve gait in older adults
Publications

Collaborating PI: Prof. Jeffrey Ojemann M.D.; Tonio Ball, M.D.
Institution: University of Washington, Uniklinik Freiburg (Germany)
Title of Project: Applications (EEG, tDCS, ECoG) in modeling of electrical currents in the human head
Publications

Collaborating PI: Gernot Plank, Ph.D.
Institution: Medical University of Graz (Austria)
Title of Project: Integration of CARP Software into Image Based Pipeline for Modeling Cardiac Electromechanics
Publications

Collaborating PI: Prof. Sabel, M.D.
Institution: University of Magdeburg (Germany)
Title of Project: Electrical stimulation of the optical system
Publications

Collaborating PI: Nicholas Schiff, M.D., Jaimie Henderson, M.D.
Institution: Weill Cornell Medical College; Stanford University
Title of Project: Deep brain stimulation (DBS) for traumatic brain injury (TBI)
Publications


Collaborating PI: Prof. Gerik Scheuermann, P.D., Dr. Thomas R. Knoesche
Institution: University of Leipzig and Max Planck Institute for Cognitive and Brain Sciences (Germany)
Title of Project: Visualizing of Electrical Fields in EEG and tDCS
Publications

Collaborating PI: Dagmar Sternad, Ph.D.
Institution: Departments of Biology, Electrical & Computer Engineering, and Physics, Northeastern University
Title of Project: Variability and stability in skill acquisition
Publications

Collaborating PI: Martin Styner, Ph.D.
Institution: Departments of Computer Science and Psychiatry, University of North Carolina Chapel Hill
Title of Project: Cortical correspondence using entropy-based particle systems and local features
Publications

Collaborating PI: Simon Warfield Ph.D. and Damon Hyde, Ph.D.
Institution: Computational Radiology Laboratory, Boston Children's Hospital, Harvard Medical School
Title of Project: Improved Source Localization for Pediatric Epilepsy
Publications

Collaborating PI: Carsten Wolters, Ph.D.
Institution: University of Munster (Germany)
Title of Project: Technical collaboration for brain source localization software
Publications

Biomedical Research Cluster 4: Cardiac Arrhythmias and Ischemia Collaborators

Collaborating PI: Tom Pilcher, Ph.D.
Institution: Primary Children's Hospital, University of Utah
Title of Project: Simulation of defibrillation in patients with congenital abnormalities and thoracic metal
Publications

Collaborating PI: Petr Stovicek,Ph.D.
Institution: Charles University Hospital, Prague (Czech Republic)
Title of Project: New Technology of Navigation and Guidance in Cardiac Arrhythmia
Publications

Collaborating PI: Peter van Dam, Ph.D.
Institution: Radboud University (Netherlands)
Title of Project: Rapid generation of clinical models for cardiac inverse problems
Publications

Collaborating PI: Linwei Wang, Ph.D.
Institution: Computing and Information Sciences, Rochester Institute of Technology
Title of Project: Transmural electrophysiological and electromechanical imaging of the heart
Publications



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Past CIBC Collaborators

Collaborating PI: Dr. John Bridge
Institution: University of Utah
Title of Project: Confocal Fluorescence Microscopy of Cardiac Myocytes
Publications

Collaborating PI: Dr. George Chen
Institution: Harvard Medical School
Title of Project: Advanced Four-Dimensional Visualization and Imaging for Radiation Oncology

Collaborating PI: Chi-Bin Chien, Ph.D.
Institution: Department of Neurobiology and Anatomy
Title of Project: Interactive visualization of multichannel confocal microscopy data in neurobiology research
Publications

Collaborating PI: Chi-Bin Chien, Ph.D.
Institution: University of Utah
Title of Project: Serial-Section Electron Microscopy for Analysis of Organization of Retinal Axons

Collaborating PI: Ed DiBella, Ph.D.
Institution: Utah Center for Advanced Imaging Research, University of Utah
Title of Project: MRI Imaging of Cardiac Perfusion
Publications

Collaborating PI: Charles DiMarzio, Ph.D, and Milind Rajadhyaksha, Ph.D.
Institution: Northeastern University
Title of Project: Computational Microscopy of Skin Simulations
Publications

Collaborating PI: Charles DiMarzio
Institution: Department of Electrical and Computer Engineering
Collaborating PI: Milind Rajadyhaksha
Institution: Dermatology Service, Northeastern University, Boston, MA
Collaborating PI: Memorial Sloan
Institution: Kettering Cancer Center, New York, NY
Title of Project: Confocal Imaging of Skin and the Oral Cavity
Publications

Collaborating PI: Craig Henriquez, Ph.D.
Institution: Department of Bioengineering, Duke University
Title of Project: Integration of cardiowave and SCIRun
Publications

Collaborating PI: Rok Hren
Institution: Institute of Mathematics, Physics and Mechanics, University of Ljubljana, Slovenia
Title of Project: Evaluation of Inverse Solution Approaches
Publications

Collaborating PI: David Isaacson, Ph.D.
Institution: Rensselaer Polytechnic Institute (RPI)
Title of Project: Torso Volume and Breast Cancer Imaging with Electrical Impedance Tomography
Publications

Collaborating PI: Allan Johnson, Ph.D.
Institution: Duke University
Title of Project: Multi-dimensional Bioelectric mapping of Mouse Models of Cardiac Disease

Collaborating PI: Prof. Charles Keller
Institution: University of Texas at San Antonio
Title of Project: Computed Tomographic Imaging Blood Vessel in Transgenic Mouse Models for Human Tumors
Publications

Collaborating PI: Dr. Dirar Khoury
Institution: Baylor College of Medicine
Title of Project: Integrated Intracardiac Ultrasound and Electrical Imaging

Collaborating PI: Ron Kikinis, M.D.
Institution: Surgical Planning Laboratory, Harvard University
Title of Project: Volume Rendering Support for Slicer

Collaborating PI: Dr. Ron Kikinis
Institution: Harvard Medical School
Title of Project: Multi-Modal Volume Rendering and Segmentation

Collaborating PI: David Laidlaw, Ph.D.
Institution: Brown University
Title of Project: Diffusion Tensor Imaging
Publications

Collaborating PI: Janet Lainhart, M.D.; Mark Leppert, Ph.D.
Institution: Departments of Psychiatry and Genetrics, University of Utah
Title of Project: Image-Based, Intermediate Biological Phenotypes Associated with Autism Spectrum Disorder

Collaborating PI: Miriam Leeser, Ph.D.
Institution: Electrical and Computing Engineering, Northeastern University
Title of Project: Middleware layer for seamless runtime porting of SCIRun computations to streaming architecture

Collaborating PI: Leslie M. Loew
Institution: University of Connecticut Health Center
Title of Project: Three-Dimensional Image Analysis and Visualization Capabilities within Virtual Cell

Collaborating PI: Robert Marc, Ph.D.; Bryan Jones, Ph.D.; James Anderson
Institution: Moran Eye Center, University of Utah
Title of Project: Serial section microscopy for discovering the circuitry of the mammalian retina
Publications

Collaborating PI: Cameron McIntyre, Ph.D.
Institution: Cleveland Clinic, Lerner College of Medicine
Title of Project: Systems-Level Model of Deep Brain Stimulation

Collaborating PI: Scott Makeig, Ph.D.
Institution: Swartz Center for Computational Neuroscience, University of California San Diego
Title of Project: Estimation to Improve Source Localization
Publications

Collaborating PI: Prof. Robert Marc
Institution: University of Utah
Title of Project: Serial-Section Electron Microscopy for Analysis of Ganglion Connectivity
Publications

Collaborating PI: Andrew McCulloch, Ph.D.
Institution: University of California, San Diego
Title of Project: Modeling and Simulation with Higher-Order Finite Elements
Publications

Collaborating PI: Prof. Alonso Moreno
Institution: University of Utah
Title of Project: Visualization and Simulation of Activation in Transgenic Mouse Hearts

Collaborating PI: Sinan Muftu, Associate Professor
Institution: Department of Mechanical and Industrial Engineering, Northeastern University, Boston, MA
Title of Project: Biomechanical Modeling of the Mandible and Teeth 

Collaborating PI: Dr. Steven Peltier
Institution: UCSD
Title of Project: Bridging the BioPSE Environment with the Telescience Grid

Collaborating PI: Joe Piven, M.D.; Heather Hazlatt, Ph.D.
Institution: Department of Psychiatry, University of North Carolina
Title of Project: Morphological analysis of neuroimages in pediatric autism
Publications

Collaborating PI: Andrew Pullan, Ph.D.
Institution: Auckland Bioengineering Institute, University of Aukland, New Zealand
Title of Project: Simulation of bioelectric fields
Publications

Collaborating PI: Petr Stovicek
Institution: Charles University Hospital, Prague, Czech Republic
Title of Project: Clinical Application of Electrocardiographic Inverse Solution
Publications


Collaborating PI: Martin Styner, Ph.D.
Institution: Departments of Computer Science and Psychiatry, University of North Carolina Chapel Hill
Title of Project: Cortical Correspondence Using Entropy-Based Particle Systems and Local Features
Publications



Collaborating PI: Bruno Taccardi, Ph.D.
Institution: CVRTI, University of Utah
Title of Project: Visualization of Cardiac Currents
Publications

Collaborating PI: Dr. Paul Thompson
Institution: UCLA
Title of Project: Collaborative Project on Visualization of Brain Variability
Publications

Collaborating PI: Matthew Tocheri
Institution: Smithsonian Institute
Title of Project: Shape-based analysis of hominid trapezia

Collaborating PI: Art Toga, Ph.D.
Institution: USC
Title of Project: Integration of SCIRun with the LONI Pipeline
Publications

Collaborating PI: Joseph Tranquillo, Ph.D.
Institution: Biomedical and Electrical Engineering, Bucknell University
Title of Project: Non-linear Coupled Neural Models
Publications

Collaborating PI: David S. Tuch
Institution: Harvard Medical School
Title of Project: Biophysical Modeling of Diffusion Anisotropy in Nerve Tissue
Publications

Collaborating PI: Simon Warfield
Institution: Harvard Medical School / Massachusetts Institute of Technology
Title of Project: Pediatric Epilepsy Surgical Planning

Collaborating PI: Carl-Fredrik Westin, Ph.D.
Institution: Laboratory of Mathematics in Imaging, Harvard Unviersity
Title of Project: Diffusion Tensor Analysis, Tracking, and Visualization
Publications

Collaborating PI: Raimond Winslow, Ph.D.
Institution: Johns Hopkins University
Title of Project: Identifying and Quantifying Shape Features of Human Left Ventricular Remodeling
Publications

Collaborating PI: Carsten Wolters, Ph.D.
Institution: University of Münster
Title of Project: Technical Collaboration for Brain Source Localization Software 

Collaborating PI: Dr. Stephen Wong
Institution: Harvard Medical School
Title of Project: Diffusion Tensor Image Analysis in the Study of Age-Related Neurodegeneration

Collaborating PI: Gregory A. Worrell, M.D., Ph.D.
Institution: Mayo Clinic Rochester and Mayo Clinic College of Medicine
Title of Project: Biomarkers of the epileptic brain
Publications


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