The Center for Integrative Biomedical Computing (CIBC) is dedicated to producing open-source software tools for biomedical image-based modeling, biomedical simulation and estimation, and the visualization of biomedical data. The Center works closely with software users and collaborators in a range of scientific domains to produce user-optimized tools and provides advice, technical support, workshops, and education to enhance user success. Biological projects and collaborations drive our development efforts, all with a single unifying vision: to develop the role of image-based modeling and analysis in biomedical science and clinical practice.